Friday, December 28, 2007

The vulnerable end of dealing in drugs

South China Morning Post (subscription) - Hong Kong And no one knows that
better than investors in drugs and biotech companies.
In 2004, when the world worried about an outbreak of avian influenza, ...

http://www.scmp.com/vgn-ext-templating/v/index.jsp?vgnextoid=b43f7fb1ecab61
10VgnVCM100000360a0a0aRCRD&s=Business&ss=Your+Money

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usiness%26ss%3DYour%2BMoney


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Thursday, December 27, 2007

Biotech Bizz: White Coats With Blue Collars

Worcester Business Journal -
Worcester,MA,USA His casino proposal is mired in political and social
deadlock, his clean energy act faces a funding crunch, and his $1 billion
biotech initiative hasn't ...

http://wbjournal.com/j/index.php?option=com_content&task=view&id=2926&Itemi
d=139

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Wednesday, December 26, 2007

Japan's Eisai to buy US MGI Pharma for $3.9 bln Reuters

USA The planned
purchase of the cancer specialist is the latest example of accelerating M&A
in the biotechnology sector, which has seen a scramble by drugmakers ...

http://www.reuters.com/article/health-SP/idUSTKV00291420071210

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Friday, December 21, 2007

Japan's Eisai to buy US MGI Pharma for $3.9 bln Washington Post

Japan's Eisai to buy US MGI Pharma for $3.9 bln Washington Post - United
States Big-ticket biotech deals this year include astrazeneca buying
medimmune for $15.6 billion and Celgene acquiring Pharmion , a rival of MGI, for $2.9
billion. ...

http://www.washingtonpost.com/wp-dyn/content/article/2007/12/10/AR200712100
0176.html

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Thursday, December 20, 2007

Chemdiv and Siwa Biotech Announce Discovery Collaboration

Chemdiv and Siwa Biotech Announce Discovery Collaboration PR Newswire (press
release) - New York,NY,USA The collaboration provides Siwa Biotech with
access to chemdiv's expertise in chemistry systems and lead discovery.
Financial terms of the collaboration ...

http://www.prnewswire.com/cgi-bin/stories.pl?ACCT=104&STORY=/www/story/12-1
0-2007/0004719581&EDATE=

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Wednesday, December 19, 2007

Genzyme CEO says biotech firm is not for sale

Genzyme CEO says biotech firm is not for sale: WSJ Washington Post - United
States NEW YORK (Reuters) - Biotechnology company Genzyme Corp (GENZ.O) is
not for sale, despite recent interest from financier Carl Icahn, the
company's chief ...

http://www.washingtonpost.com/wp-dyn/content/article/2007/12/06/AR200712060
0184.html

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Tuesday, December 18, 2007

Oxford Finance Corporation and GE Healthcare Financial Services

PR Newswire (press release) - New York,NY,USA Astex Therapeutics, based in
Cambridge, England, is one of the largest privately-held biotech companies
in the UK, concentrating on the discovery and ...

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0-2007/0004719936&EDATE=

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Friday, December 14, 2007

French activist Bove to go on anti-GMO hunger strike

French activist Bove to go on anti-GMO hunger strike Reuters - USA In an
attempt to calm these concerns, France last week formally suspended the
commercial use of GMO seeds until February 9 and ordered a biotech safety
...

http://www.reuters.com/article/environmentNews/idUSL1011368420071210

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Thursday, December 13, 2007

Sensecam Aids Patients with Memory Problems Slashdot

USA It was tagged "biotech" then too. This is not biotech any more than the mouse on your computer is biotech or the shirt on your back is biotech. ...

http://science.slashdot.org/article.pl?sid=07/12/10/1510221

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Wednesday, December 12, 2007

Prostate Cancer

12-11-2007

PHOENIX, AZ, DECEMBER 11, 2007-Results from two genome-wide association
studies have identified a genetic variant of the DAB2IP gene that is
associated with the risk of aggressive prostate cancer. Research teams from
the Translational Genomics Research Institute (TGen), Wake Forest University
School of Medicine, the Karolinska Institute in Stockholm, Sweden, and Johns
Hopkins Medical Institutions made the discovery jointly.

Researchers suspect that the DAB2IP gene is involved in tumor suppression,
suggesting that this protective mechanism goes awry in men with the variant
form. The finding, reported today in the Journal of the National Cancer
Institute, might one day help doctors tailor treatment based on a patient's
genetic makeup.

Both genetic and environmental factors are important in the development of
prostate cancer, and it is only recently that some of the consistent genetic
factors have been identified. It is not clear at present whether men who are
genetically prone to the disease tend to have more aggressive disease than
men who are not.

"Because there is no way to tell whether a person has or will have the
aggressive version versus the mild version of prostate cancer, both forms
are treated the same-with radiotherapy or surgery to remove the prostate
gland. The identification of this genetic variant could lead to better risk
assessment for aggressive disease, providing doctors with more information
on how to best treat men who may be diagnosed with prostate cancer," said
John Carpten, Ph.D., director of TGen's Division of Integrated Cancer
Genomics and senior author of the paper.

Analysis of 3,159 samples led the researchers to conclude that men
possessing the DAB2IP variant appear to carry a nearly 36 percent increased
risk of advanced prostate cancer.

"In most cases, prostate cancer is not a death sentence, but it would be
ideal to identify men with an aggressive form of disease," said Jianfeng Xu,
M.D., Dr.PH, a senior author and a professor of epidemiology and cancer
biology at Wake Forest University School of Medicine. "Our finding suggests
the possibility of developing a blood test to gauge disease type so doctors
could decide if more aggressive treatment is needed."

The researchers screened DNA samples from 500 men with advanced prostate
cancer and 500 healthy men of the same age in Sweden. This DNA screening
examined the entire genome for more than 550,000 single nucleotide
polymorphisms (SNPs), which are locations on chromosomes where a single unit
of DNA, or genetic material, may vary from one person to the next. The team
then focused on 60,000 SNPs that have also been evaluated by a similar study
conducted by the National Cancer Institute (NCI) called Cancer Genetic
Markers of Susceptibility (CGEMS). Evaluation of these 60,000 SNPs
identified seven SNPs that appeared to be linked to disease aggressiveness.

Additionally, researchers screened another 1,242 men with advanced disease
and 917 healthy men who were part of a research project at Johns Hopkins
Medical Institutions. This group included both African and European
Americans. Through these multiple screenings, the researchers found that the
variant form of DAB2IP is associated with an increased risk of having
aggressive disease.

Senior authors Henrik Gronberg, M.D., Ph.D., a professor of epidemiology
from Karolinska Institute, and William Isaacs, Ph.D., a professor of urology
at Johns Hopkins Medical Institutions, both agree that the findings were
possible because advances in technology allow researchers to take a more
systematic approach to looking at the entire genome. Instead of solely
studying genes that they suspect may be related to disease susceptibility,
they can study the entire genome and look for associations.

"By using state-of-the-art technologies, we can find genes that were not
previously known or thought to be involved with disease risk," said David
Duggan, Ph.D., an Investigator in TGen's Genetic Basis of Human Disease
Division. "If we can then learn more about the proteins they produce, it
could lead to new understanding about disease mechanisms and new
treatments."

Co-first authors on the paper were TGen's Duggan and Siqun Lilly Zheng,
M.D., from Wake Forest.

About TGen
The Translational Genomics Research Institute (TGen), a non-profit 501(c)(3)
organization, is focused on developing earlier diagnoses and smarter
treatments. Translational genomics research is a relatively new field
employing innovative advances arising from the Human Genome Project and
applying them to the development of diagnostics, prognostics and therapies
for cancer, neurological disorders, diabetes and other complex diseases.
TGen's research is based on personalized medicine and the institute plans to
accomplish its goals through robust and disease-focused research.

About Wake Forest University Baptist Medical Center
Wake Forest University Baptist Medical Center is an academic health system
comprised of North Carolina Baptist Hospital and Wake Forest University
Health Sciences, which operates the university's School of Medicine. U.S.
News & World Report ranks Wake Forest University School of Medicine 18th in
family medicine, 20th in geriatrics, 25th in primary care and 41st in
research among the nation's medical schools. It ranks 35th in research
funding by the National Institutes of Health. Almost 150 members of the
medical school faculty are listed in Best Doctors in America.


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Tuesday, December 11, 2007

The Quigley Corporation to Present at NYSSA Biotech/Specialty ...

Reuters - USA
... at the New York Society of Security Analysts, (NYSSA) 11th Annual
Biotech/Specialty Pharma Conference in New York City on Tuesday, December
11, 2007. ...

http://www.reuters.com/article/pressRelease/idUS232218+06-Dec-2007+PRN20071
206

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Monday, December 10, 2007

Vic Govt's GM adviser denies conflict of interest

ABC Online - Australia "We do have a small number of clients that are biotech start-up companies, small and usually rather impecunious companies. One of those is an agricultural...

http://www.abc.net.au/news/stories/2007/12/06/2111997.htm

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Friday, December 07, 2007

Hemispherx Biopharma to Present At the NYSSA 11th Annual Biotech ...

CNNMoney.com - USA
... Analysts 11th Annual Biotech/Specialty Pharma Conference located at
1177 Avenue of the Americas in New York City scheduled for December 11 - 12,
2007. ...

http://money.cnn.com/news/newsfeeds/articles/primenewswire/132628.htm

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Thursday, December 06, 2007

Comment on The new faces of Silicon Valley: biotech-savvy co ...

By friend
I've known Linda for over 20 years and she's long had a passion for
genetics. She wrote kids books about genetics in the mid-90's when her kids
were in grade school, and, as far as I know, had a lot of the "real ideas"
for the company ...

http://pimm.wordpress.com/2007/11/18/the-new-faces-of-silicon-valley-biotec
h-savvy-co-founders-avey-wojcicki/#comment-44473

Comments for Pimm - Partial immortali...
http://pimm.wordpress.com


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Wednesday, December 05, 2007

Yep, organize your PDF files with CC licenses!

By Ricardo Vidal
From time to time I see an app that just makes me want to purchase a Mac.
Some time back I wrote a post about a fantastic app called Papers that was
the perfect app to organizer... err... papers! (Winner of the
2007 Apple Design Award for ...

http://my.biotechlife.net/2007/11/18/yep-organize-your-pdf-files-with-cc-li
censes/

My Biotech Life
http://my.biotechlife.net


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Tuesday, December 04, 2007

'Ethical issues raised by biotech need to be addressed'

Hindu - Chennai,India
The symposium was organised by the National Institute of Animal Nutrition
and Physiology (NIANP) and the Association of Biotechnology-led Enterprises
(ABLE) ...

http://www.hindu.com/2007/11/18/stories/2007111853420400.htm

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Monday, December 03, 2007

Pharma, biotech cos bet big on insulin therapy Times of India

India NEW DELHI: The $100-million domestic insulin therapy market is expected to
attain a size of $1 billion over 10 years, with biotech companies such as
Biocon ...

http://timesofindia.indiatimes.com/Business/India_Business/Pharma_biotech_c
os_bet_big_on_insulin_therapy/articleshow/2550996.cms

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