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Thursday, October 06, 2005
 
[ biotech news ] W. L. Gore & Associates Acquires Premier Bioactive Heparin Technology Company

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W. L. Gore & Associates Acquires Premier Bioactive Heparin
Technology Company

FLAGSTAFF, Ariz Oct. 5, 2005--W. L. Gore & Associates Inc. (Gore)
announced today that it has acquired Carmeda AB, a Sweden-based
manufacturer of the most clinically proven, hemocompatible surface
coating for medical devices. Carmeda has been a strategic supplier
to Gore of heparin and heparin-related technologies for nearly 10
years. Financial details and other terms of the agreement are
confidential. The Carmeda AB leadership team and work force will
remain in its existing facility in Upplands Vasby, Sweden.

The Carmeda(R) BioActive Surface (CBAS(R)) mimics the non-
thrombogenic properties of the endothelial lining of blood vessels
using a patented "end-point attachment" covalent bonding of heparin.
No other biologically active coating demonstrates the well-
documented long-term bioactivity of CBAS. The unique CBAS chemistry
enables the immobilized heparin on the device surface to reduce
thrombogenicity. Thus, CBAS expresses stable, antithrombotic
activity and avoids the "dosing" resulting from the leaching heparin
technologies.

Gore utilizes the CBAS coating in its GORE-TEX(R) PROPATEN Vascular
Graft. The CBAS coating provides unique hemocompatibility by
minimizing clot formation on the inside surface of GORE-TEX PROPATEN
Vascular Grafts. Such clots can result in blockages that can reduce
blood flow through the grafts and may require clinical intervention.
The GORE-TEX PROPATEN Vascular Graft is commercially available to
physicians in Europe and elsewhere outside the United States. It is
an investigational device in the United States, limited by U.S. law
to investigational use only. A U.S. clinical study under a Food &
Drug Administration (FDA) IDE is currently in progress.

John Sininger, leader of the Gore Medical Products Division,
stated, "At the heart of Gore's interest in Carmeda is our
comprehensive strategy for growing our business and expanding
offerings in the medical products marketplace. Part of that strategy
involves strategic acquisitions of companies that share our
commitment to applying product technologies that make a difference
in the lives of patients. Carmeda is just such a company."

"We are very excited at the prospects for the winning combination of
two premier biomedical technologies, bioactive heparin and ePTFE,
for improving medical device performance and positively impacting
patients' lives," said Paul Begovac, Ph.D., technology leader at
Gore. "We are confident that, together with Carmeda, we can continue
to offer our customers the finest and most innovative cardiovascular
products."

About Gore & Associates

The Gore Medical Products Division has provided creative therapeutic
solutions to complex medical problems for three decades. During that
time, more than 13 million innovative Gore Medical Devices have been
implanted, saving and improving the quality of lives worldwide. The
extensive Gore Medical family of products includes vascular grafts,
endovascular and interventional devices, surgical meshes for hernia
repair and sutures for use in vascular, cardiac, general surgery and
orthopedic procedures. Gore was recently named the second best
company to work for by Fortune Magazine. The company's Medical
Products Division is celebrating its 30-year anniversary worldwide
throughout 2005.

Products listed may not be available in all markets pending
regulatory clearance.

GORE, GORE-TEX(R) and PROPATEN are trademarks of W. L. Gore &
Associates Inc.

Carmeda(R) BioActive Surface and CBAS(R) are trademarks of Carmeda
AB.

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