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Monday, August 29, 2005
 
[ biotech news ] SciFinder 2006 launches powerful new substance search capablities

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SciFinder 2006 launches powerful new substance search capablities

Washington, D.C., August 28, 2005 - Building upon a decade of
innovation, the new SciFinder 2006 advances its reputation as an
essential information tool and part of the process of chemical and
pharmaceutical research. For the first time, scientists exploring
the CAS Registry of 26 million organic and inorganic chemical
substances can retrieve "similar substances" to foster new ideas and
directions in drug discovery and other fields of scientific
inquiry. "Similarity Searching" is only one of several new features
adding new power and depth to SciFinder this year. CAS, a division
of the American Chemical Society, launched SciFinder 2006 and
SciFinder Scholar 2006 this week at the American Chemical Society
meeting in Washington, D.C.

SciFinder provides similarity searching of CAS registry
Washington, D.C., August 28, 2005 - Building upon a decade of
innovation, the new SciFinder 2006 advances its reputation as an
essential information tool and part of the process of chemical and
pharmaceutical research. For the first time, scientists exploring
the CAS Registry of 26 million organic and inorganic chemical
substances can retrieve "similar substances" to foster new ideas and
directions in drug discovery and other fields of scientific
inquiry. "Similarity Searching" is only one of several new features
adding new power and depth to SciFinder this year. CAS, a division
of the American Chemical Society, launched SciFinder 2006 and
SciFinder Scholar 2006 this week at the American Chemical Society
meeting in Washington, D.C.
Nobel Laureate, Dr. K. Barry Sharpless, W. M. Keck Professor of
Chemistry at the Scripps Research Institute, shared his reflections
regarding the significance of SciFinder:

"We were using SciFinder at Scripps even before SciFinder Scholar
was invented," said Dr. Sharpless. "I am a big user and don't see
how any researcher could hope to excel without daily, round-the-
clock access. In the old days, you could be forgiven for not knowing
about a certain paper, but now there is no excuse. The speed and
scope of its search power is amazing, and the answer to 'what aspect
is most helpful for you?' could be as diverse as the users. In my
case, SciFinder enhances my reactivity insights, making it easier
to 'see' those ill-defined boundaries where important new phenomena
are lurking."

New features of SciFinder 2006 include:

Similarity Searching - as a complement to SciFinder substructure
searching, similarity searching permits new options for identifying
substances of interest via precise statistical analysis using the
Tanimoto algorithm;

Structure Query Tools - to identify substances more precisely, new
tools permit drawing a variable attachment point and a repeating
group;

Reaction Searching - finding reaction information has been enriched
with new content and features; these include reaction conditions and
identifying intermediate reactions in a multi-step reaction.
Scientists can also click any substance in the reaction display to
find additional information, including retro-synthetic pathways;

Navigation & Usability - improvements include duplicate detection
and removal for more efficient combined searching of the CAplus and
MEDLINE databases. A new Locate feature permits quick access to
journal and patent documents by entering journal titles, author
names and other partial bibliographic information.
While announcing the release of SciFinder 2006 for Windows, CAS
revealed that a native MAC OS X version of SciFinder will appear in
fourth quarter 2005.

SciFinder was created in 1995 with the vision of providing
scientists easy, point-and-click access to chemical information. The
new intelligent research tool -- a client-server product for the
desktop -- was an immediate hit with scientists, assisting them and
other researchers worldwide with access to the multidisciplinary CAS
databases. Today, tens of thousands of scientists at pharmaceutical,
biotech and chemical companies around the world use SciFinder
regularly to explore research topics, browse scientific journals and
stay up-to-date on recent scientific developments. SciFinder Scholar
was introduced in 1998 to serve the needs of campus-wide searching
in academia and now serves more than 1,000 institutions of higher
learning worldwide.

###
CAS, a division of the American Chemical Society, provides the
world's largest and most current collection of chemical and related
scientific information, including the most authoritative database of
chemical substances, the CAS Registry. CAS combines these databases
with advanced search and analysis technologies to deliver the most
complete and effective digital information environment for
scientific research and discovery, including such products as
SciFinder, SciFinder Scholar, STN, STN Express and STN AnaVist,
among others. The CAS web site is at www.cas.org.

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